Agent: Biomni

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Biomedical Research AI Agent with Biomni

Best for: biomedical research ai agent

Biomni is a general-purpose biomedical AI agent that autonomously executes complex research workflows across diverse biomedical domains.

Run broad biomedical research tasks with an agent designed for multi-step scientific workflows.

Biomni is a general-purpose AI research assistant for biomedicine. It can help scientists plan and run complex research workflows across many areas of biology and medicine by combining literature/tool retrieval, reasoning, and code execution. Instead of relying on fixed templates, Biomni can assemble multi-step analyses dynamically, making it useful for tasks such as gene prioritization, drug repurposing, rare disease investigation, microbiome analysis, and protocol generation from real-world biomedical data.

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20minds Co-Scientist workspace showing agent output, code, and controls

Example prompts you can run

QUESTION

🧬 For chronic myeloid leukemia (CML), return: 1) the hallmark fusion gene, 2) the chromosome translocation, 3) the first FDA-approved targeted drug for CML and its first approval year.

EXPECTED ANSWER

Fusion gene: BCR-ABL1 Translocation: t(9;22) (Philadelphia chromosome) First targeted drug: imatinib (Gleevec) FDA, first approval year: 2001

QUESTION

🦠 Create a mechanism-to-treatment summary for Methicillin-resistant Staphylococcus aureus (MRSA): 1) resistance gene, 2) altered protein target, 3) why most beta-lactams fail, 4) one beta-lactam that can still treat MRSA.

EXPECTED ANSWER

Resistance gene: mecA Altered target: PBP2a (penicillin-binding protein 2a) Failure reason: PBP2a has low affinity for most beta-lactam antibiotics Active beta-lactam: ceftaroline

Details

  • License: Apache-2.0
  • Citation: Huang et al. (2025). Biomni: A General-Purpose Biomedical AI Agent. bioRxiv preprint.
  • Models: gpt-5.4, gpt-5.4-mini, gpt-5, gpt-5-mini, claude-opus-4-7, claude-sonnet-4-6, claude-haiku-4-5

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